Three new polyribonucleotides, poly (3-deazauridylic acid), poly (2-fluoroinosinic acid) and “poly (ribavirinic acid)” were synthesized. These compounds were designed to explore the importance and limits of the acidic properties of putative Watson-Crick hydrogen bonding protons in forming duplexes with complementary polynucleotides. None of these polymers formed such duplexes, thus establishing that a limited range of acidities is required.
No takes yet. Share an insight, caveat, or question.
Amarnath et al. (1982) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: