O-methyl (3′-6) and (5′-6) thymidinyl gluco-and mannopyranosides and (3′-6) thymidinyl glucofuranose can be synthesised in excellent yields by applying the phosphotriester method. The lipophilic phosphotriesters thus obtained are designed as carriers of nucleoside drugs across cellular membranes.
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Belsito et al. (1999) studied this question.
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