January 1, 2003Arthritis & Rheumatism
Concomitant disappearance of electrocardiographic abnormalities and of acquired maternal autoantibodies during the first year of life in infants who had QT interval prolongation and anti‐SSA/Ro positivity without congenital heart block at birth
Population
Infants who had QT interval prolongation and anti-SSA/Ro positivity without congenital heart block at birth
Design
Cohort
Follow-up
first year of life
Authors
Discussion
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Implication
Transient ECG changes in anti-SSA/Ro-exposed infants without CHB may resolve spontaneously; leaves open whether autoantibody clearance drives normalization.
Structured PICO
P
Population
Infants who had QT interval prolongation and anti-SSA/Ro positivity without congenital heart block at birth
O
Outcome
Disappearance of electrocardiographic abnormalities and acquired maternal autoantibodiessurrogate
In infants with QT prolongation and anti-SSA/Ro positivity but no congenital heart block, ECG abnormalities resolve alongside the clearance of maternal autoantibodies during the first year of life.
Cite This Study
Cimaz et al. (2003) studied this question.