Acute febrile neutrophilic dermatosis (Sweet's syndrome): a study of 15 cases in Iran

BACKGROUND: Sweet's syndrome is well recognized by dermatologists and is not infrequently diagnosed in Iran; however, few case series have been reported. METHODS: A clinicopathologic study was carried out on 15 cases of Sweet's syndrome in Hamedan, in the west of Iran, between 1994 and 2004. RESULTS: The incidence of Sweet's syndrome was 3 per 10,000 amongst new dermatologic patients. All were women with a mean age of 58 years. All 15 cases were of the classic type, with no associated diseases. Fever was seen in only six (40%) patients. CONCLUSIONS: Sweet's syndrome has a broad spectrum of clinical and pathologic findings in various areas of the world. Further investigation is necessary to determine the etiology and effect of environmental factors in this disease.