Why the study?
Do age, gender, indication for surgery, bilateral internal carotid artery disease, hypertension, and smoking predict perioperative outcomes following carotid endarterectomy?
Do age, gender, indication for surgery, bilateral internal carotid artery disease, hypertension, and smoking predict perioperative outcomes following carotid endarterectomy?
Traditional clinical variables such as age, gender, hypertension, and smoking did not significantly predict perioperative mortality or stroke following carotid endarterectomy in this cohort.
The quoted combined mortality and morbidity following carotid endarterectomy is about 5-7%. In an attempt to identify a subgroup of high risk patients, a review has been undertaken of 404 carotid endarterectomies performed between January 1985 and March 1994. The perioperative mortality rate was 2%, with 3.4% of patients experiencing transient neurological deficits and 4% permanent strokes. Multiple logistic regression analysis was used to estimate the influence on outcome of age, gender, indication for surgery, bilateral internal carotid artery disease, hypertension and smoking. No significant explanators were identified.
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Alun H. Davies (1996) studied this question.
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