Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
December 2, 2002Journal of Medicinal Chemistry

First X-ray Cocrystal Structure of a Bacterial FabH Condensing Enzyme and a Small Molecule Inhibitor Achieved Using Rational Design and Homology Modeling

View Full Paper
Ask AI
Bookmark
Share

Authors

RDR. A. DAINESNew FrontierIPIsrail PendrakNew FrontierKSKelvin ShamAmgen (United States)

Discussion

Loading...

Member takes

Implication

Key Points

Key points are not available for this paper at this time.

Cite This Study

DAINES et al. (2002) studied this question.

synapsesocial.com/papers/6a7998e302ab7a73dd02705ehttps://doi.org/10.1021/jm025571b
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Regulation of fatty acid biosynthesis in Escherichia coli1993 · 598 citations
  2. 2Identification, Substrate Specificity, and Inhibition of theStreptococcus pneumoniae β-Ketoacyl-Acyl Carrier Protein Synthase III (FabH)2001 · 99 citations
  3. 3Purification and characterization of 3-ketoacyl-acyl carrier protein synthase III from spinach. A condensing enzyme utilizing acetyl-coenzyme A to initiate fatty acid synthesis.1992 · 120 citations