Mediastinal irradiation can rarely lead to critical stenosis of the aortic and mitral valves, highlighting the need for awareness of this complication.
Supports vigilance for radiation-related valvular disease in survivors; leaves open need for prospective incidence and screening studies.
Radiotherapy is used widely in cancer treatment. Mediastinal irradiation is associated with valvular regurgitation; however, stenosis is rare. We present a patient with critical aortic and mitral valve stenosis after mediastinal irradiation and discuss the natural history, treatment, and prognosis of radiation‐associated valvular heart disease. Catheter Cardiovasc Interv 2004;63:247–250.
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Adabağ et al. (2004) studied this question.
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