Pathogenetic significance of oxidative stress in canine prostatic hyperplasia

Canine prostatic hyperplasia is a common disease, mainly in older males, which is registered in animals regardless of breed, fatness and other factors. The pathogenesis of this disease in dogs is not well studied. One of its components – hormonal changes, has been studied in more depth, as a result of which it is known that the development of prostatic hyperplasia occurs due to impaired androgenesis, changes in the testosterone-estradiol ratio. On the contrary, data on the redox balance in prostate tissue during hyperplastic changes are scarce.