What question did this study set out to answer?

To determine whether varying degrees of atherosclerosis in the descending aorta evaluated by transesophageal echocardiography independently predict neurologic and cardiac outcomes following coronary artery bypass grafting.

October 1, 1996Anesthesia & Analgesia

Severity of Aortic Atheromatous Disease Diagnosed by Transesophageal Echocardiography Predicts Stroke and Other Outcomes Associated with Coronary Artery Surgery

View Full Paper

Ask AI

Bookmark

Why the study?

Does the severity of aortic atheromatous disease diagnosed by TEE predict stroke and death in patients undergoing CABG?

Population

189 patients undergoing elective CABG who participated in a randomized controlled trial of low or high mean…

Comparison

Higher grades of aortic atheromatous disease of… vs Lower grades of aortic atheromatous disease.

Design

Cohort, Aortic atheromatous disease was graded by observers blinded to outcome.

Follow-up

6 months

Authors

GHGregg S. HartmanDartmouth–Hitchcock Medical Center FYFun-Sun F. YaoUniversidad Mayor MBMathias BruefachCornell University

Discussion

Member takes

Implication

May inform TEE-based risk stratification in CABG; leaves open whether grade-targeted interventions reduce stroke or death.

Key Points

To determine whether varying degrees of atherosclerosis in the descending aorta evaluated by transesophageal echocardiography independently predict neurologic and cardiac outcomes following coronary artery bypass grafting.
Conducted intraoperative transesophageal echocardiography of the descending aorta in 189 of 248 patients enrolled in a randomized controlled trial testing low (50–60 mm Hg) versus high (80–100 mm Hg) mean arterial pressure during cardiopulmonary bypass for elective bypass surgery.
Graded aortic atheromatous disease from I to V by outcome-blinded observers, monitoring death, stroke, and major cardiac events at 1 week and 6 months postoperatively.
At 1 week, perioperative strokes occurred in 0% (0/123) of patients with Grades I or II atheroma, compared to 5.5% (2/36) in Grade III, 10.5% (2/19) in Grade IV, and 45.5% (5/11) in Grade V (Fisher's exact test, P = 0.00001).
At 6 months, advancing aortic atheroma grade remained a significant univariate predictor of both stroke (P = 0.00001) and death (P = 0.03).

Structured PICO

Does the severity of aortic atheromatous disease diagnosed by TEE predict stroke and death in patients undergoing CABG?

Population

189 patients undergoing elective CABG who participated in a randomized controlled trial of low (50-60 mm Hg) or high (80-100 mm Hg) mean arterial pressure during cardiopulmonary bypass.

Intervention

Higher grades (III-V) of aortic atheromatous disease of the descending aorta assessed by intraoperative transesophageal echocardiography (TEE).

Comparator

Lower grades (I-II) of aortic atheromatous disease.

Outcome

Death, stroke, and major cardiac events assessed at 1 week and 6 months.hard clinical

Severity of descending aortic atheroma assessed by intraoperative TEE is a strong predictor of perioperative stroke and death in patients undergoing CABG.

Cite This Study

Hartman et al. (1996) studied this question.

synapsesocial.com/papers/6a79ad8ea51ded8e7b325169 https://doi.org/10.1213/00000539-199610000-00007

View Full Paper

Ask AI

Bookmark

Severity of Aortic Atheromatous Disease Diagnosed by Transesophageal Echocardiography Predicts Stroke and Other Outcomes Associated with Coronary Artery Surgery

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Severity of Aortic Atheromatous Disease Diagnosed by Transesophageal Echocardiography Predicts Stroke and Other Outcomes Associated with Coronary Artery Surgery

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Also Consider

Also Consider