Key result
The pooled prevalence of hypertension among people diagnosed with diabetes in Africa was 58.1%, with the highest prevalence observed in Central Africa.
Why the study?
Hypertension and diabetes frequently co-occur and increase cardiovascular disease risk and healthcare spending, but the burden of hypertension among people with diabetes in African countries needed estimation.
Meta-Analysis
Effect estimate: 58.1% (95% CI 52.0% - 63.2%)
The high pooled prevalence of hypertension (58.1%) among people with diabetes in Africa highlights the critical need for integrated service delivery to prevent cardiovascular disease.
High comorbidity burden supports integrated hypertension-diabetes screening across Africa; extends regional prevalence estimates while leaving management strategies open.
Background Hypertension and diabetes share common pathophysiological mechanisms and hence have a high likelihood of co-occurring. The co-existence of hypertension and diabetes increases cardiovascular disease risk and healthcare spending. This review aimed to estimate the burden of hypertension among people with diabetes in African countries. Methods This review was registered in the International Prospective Register of Systematic Reviews (CRD42021256221). We searched PubMed, Embase, and Hinari databases to identify peer-reviewed articles which provided data on the prevalence of hypertension in people diagnosed with diabetes in Africa. Studies included in the review used different diagnostic criteria and thresholds for hypertension and diabetes diagnosis. We quantified the prevalence of hypertension using random-effects models. We applied generalized linear mixed models with logit transformation to compute regional and overall pooled prevalence and estimate heterogeneity (I 2 ). Results Out of 3810 studies retrieved from various sources, 41 met the inclusion criteria with sample sizes ranging from 80 - 116726. The mean age was 58 (± 11) years and 56% were women. The pooled prevalence of hypertension in people diagnosed with diabetes was 58.1% [95% CI: 52.0% - 63.2%]. By African region, Central Africa had the highest hypertension prevalence; 77.6% [95% CI: 53.0% - 91.4%], South Africa 69.1% [95% CI: 59.8% - 77.1%;], North Africa 63.4% [95% CI: 37.1% - 69.1%;], West Africa 51.5% [95% CI: 41.8% - 61.1%] and East Africa 53.0% [95% CI: 45.8% - 59.1%]. Increasing age, being overweight/obese, being employed, longer duration of diabetes, urban residence, and male sex were associated with a higher likelihood of hypertension diagnosis (p-values<0.005). Conclusion The high prevalence of hypertension among people with diabetes in Africa, highlights the critical need for an integrated differentiated service delivery to improve and strengthen primary care and prevent cardiovascular disease. Findings from this meta-analysis may inform the delivery of interventions to prevent premature cardiovascular disease deaths among persons in African countries.
No takes yet. Share an insight, caveat, or question.
Hinneh et al. (2023) conducted a meta-analysis in Diabetes and Hypertension. Diabetes was evaluated on Prevalence of hypertension (58.1%, 95% CI 52.0% - 63.2%). The pooled prevalence of hypertension among people diagnosed with diabetes in Africa was 58.1%, with the highest prevalence observed in Central Africa.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: