Why the study?
Does dual-chamber pacing with proper interval programming improve symptoms and hemodynamics in patients with hypertrophic obstructive cardiomyopathy?
Does dual-chamber pacing with proper interval programming improve symptoms and hemodynamics in patients with hypertrophic obstructive cardiomyopathy?
Proper interval programming to maintain atrial contribution is critical for the success of dual-chamber pacing in hypertrophic obstructive cardiomyopathy.
Vigilant atrial capture monitoring is essential during dual-chamber pacing in HOCM; leaves open whether optimized intervals improve outcomes in prospective trials.
Beta blockers and calcium channel blockers are the mainstay of therapy for hypertrophic obstructive cardiomyopathy. Recent evidence suggests that dual-chamber pacing may also relieve symptoms in a subset of patients. Proper interval programming is critical to the success of this intervention-as well as maintenance of the atrial contribution to preserve left ventricular diastolic filling. This report illustrates the importance of atrial contribution, as well as the loss of atrial capture, which can lead to hemodynamic deterioration and recurrence of symptoms.
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Schactman et al. (1997) studied this question.
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