Why the study?
Does the presence of mitral annular calcification or aortic valve sclerosis predict incident stroke in adults free of clinical cardiovascular disease?
Does the presence of mitral annular calcification or aortic valve sclerosis predict incident stroke in adults free of clinical cardiovascular disease?
In adults free of clinical cardiovascular disease, mitral annular calcification, but not aortic valve sclerosis, is a strong independent risk factor for incident stroke.
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MAC may flag higher stroke risk in primary prevention; hypothesis-generating and requires prospective validation before guiding decisions.
Kizer et al. (2005) studied this question.
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