Surveillance report uncovers plasmid-mediated ceftazidime resistance from SHV-type beta-lactamases in imported Klebsiella pneumoniae isolates, highlighting international transmission risks.
We report the isolation of three strains of Klebsiella pneumoniae sensu lato, brought into the United Kingdom by patients from Greece and Egypt, that showed plasmid-determined resistance to ceftazidime. All three produced beta-lactamases shown by DNA hybridisation studies to belong to the SHV group. One produced an enzyme that appeared to be related to, but distinguishable from, SHV-1; another SHV-2 and the third SHV-5.
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Shannon et al. (1990) studied this question.
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