Why the study?
Is the extent of coronary artery disease associated with Alzheimer disease neuropathology in postmortem subjects?
Population
99 postmortem subjects from the Mount Sinai School of Medicine Department of Psychiatry Brain Bank, devoid…
Design
Cross-sectional
Authors
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Does not support practice change; leaves open whether CAD accelerates AD pathology in ApoE4 carriers.
Is the extent of coronary artery disease associated with Alzheimer disease neuropathology in postmortem subjects?
The severity of coronary artery disease is independently associated with Alzheimer's disease neuropathology, particularly among individuals carrying the APOE4 allele.
Beeri et al. (2006) studied this question.
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