January 1, 2002Fetal Diagnosis and Therapy

Prenatal Ultrasound May Predict Fetal Response to Therapy in Non-Hydropic Fetuses with Supraventricular Tachycardia

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Why the study?

Does the presence of tricuspid regurgitation predict poorer response to prenatal therapy in non-hydropic fetuses with supraventricular tachycardia?

Population

40 non-hydropic fetuses with supraventricular tachycardia, mean gestational age 29 +/- 4.9 weeks. 10 had…

Comparison

Prenatal antiarrhythmic therapy vs Fetuses without tricuspid regurgitation

Design

Cohort

Follow-up

Until birth

Authors

JJJean‐Marie JouannicSorbonne Université JBJ. Le BidoisHôpital Necker-Enfants Malades LFL FermontUniversité Paris-Sud

Discussion

Member takes

Implication

TR may flag fetal SVT cases needing closer monitoring or alternative agents; leaves open whether it should modify therapy protocols.

Structured PICO

Does the presence of tricuspid regurgitation predict poorer response to prenatal therapy in non-hydropic fetuses with supraventricular tachycardia?

Population

40 non-hydropic fetuses with supraventricular tachycardia (28 reciprocating SVT, 12 atrial flutter), mean gestational age 29 +/- 4.9 weeks. 10 had significant tricuspid valve regurgitation.

Intervention

Prenatal antiarrhythmic therapy (digoxin used as first-line therapy in 32 cases)

Comparator

Fetuses without tricuspid regurgitation

Outcome

Fetal response to therapy assessed by the rate of prenatal SVT reduction and the mean time interval to sinus rhythm restorationsurrogate

The presence of tricuspid regurgitation on prenatal ultrasound predicts a delayed and less successful response to antiarrhythmic therapy in non-hydropic fetuses with SVT.

Cite This Study

Jouannic et al. (2002) studied this question.

synapsesocial.com/papers/6a79c6cdfbd9051d3b0df198 https://doi.org/10.1159/000048021

Topics

Tricuspid regurgitation

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