Key result
Systematic medication review supported by collegial mentoring significantly decreased the use of antihypertensive drugs in nursing home patients without affecting systolic blood pressure (P=0.041).
Why the study?
Does systematic medication review with collegial mentoring reduce antihypertensive drug use and affect blood pressure in multimorbid nursing home patients?
RCT (n=295)
Does systematic medication review with collegial mentoring reduce antihypertensive drug use and affect blood pressure in multimorbid nursing home patients?
p-value: p=0.041
A systematic medication review with collegial mentoring can successfully deprescribe antihypertensive medications in nursing home patients without adversely affecting systolic blood pressure.
Supports deprescribing antihypertensives via medication review in multimorbid nursing home residents; challenges routine continuation endorsed by most guidelines.
BACKGROUND: It is debatable whether treating multimorbid nursing home patients with antihypertensive drugs produces beneficial effects. Most cardiovascular guidelines promote treatment; few have advice on how to deprescribe when treatment may no longer be necessary. We investigated the effect of medication review on antihypertensive drug use and the association between cognition, blood pressure, and prescribing. METHODS: = 295, 39%) were randomized to systematic medication review where the physician received support from peers (collegial mentoring) or were given care as usual (control condition). Outcome measures were the number of antihypertensive drugs, systolic blood pressure, and pulse. We used hospitalizations and deaths as criteria to assess harm. RESULTS: = 0.041). CONCLUSION: A systematic medication review supported by collegial mentoring significantly decreased the use of antihypertensive drugs in nursing home patients without an effect on the systolic blood pressure over time.
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Gulla et al. (2018) conducted an RCT in Multimorbid nursing home patients on antihypertensive drugs (n=295). Systematic medication review with collegial mentoring vs. Care as usual was evaluated on Number of antihypertensive drugs, systolic blood pressure, and pulse (p=0.041). Systematic medication review supported by collegial mentoring significantly decreased the use of antihypertensive drugs in nursing home patients without affecting systolic blood pressure (P=0.041).
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