Key result
Aortic root-sparing repair compared to root replacement yielded conflicting outcomes for mortality and re-intervention, with current literature unable to definitively support one approach.
Why the study?
Controversy exists regarding aggressive aortic root replacement versus conservative root-sparing repair, alongside valve-sparing root replacement, in acute type A aortic dissection.
Does aortic root replacement compared to root-sparing repair improve mortality and reduce re-intervention risk in patients with acute type A aortic dissection?
Does aortic root replacement compared to root-sparing repair improve mortality and reduce re-intervention risk in patients with acute type A aortic dissection?
Current literature provides conflicting evidence on whether aortic root replacement or root-sparing repair yields better outcomes in acute type A aortic dissection, leaving the decision highly dependent on surgeon preference and case-specific factors.
Retrospective data preclude favoring root-sparing repair or replacement; leaves open need for randomized trials.
Acute type A aortic dissection is a surgical emergency with a high mortality rate if left untreated. Management of the aortic root in this setting constitutes an intricate decision-making framework, further complicated by the emergent nature of the dissection. There exists much controversy regarding pursuit of the aggressive aortic root replacement versus a conservative root-sparing repair, alongside considerations for valve-sparing root replacement. In this review, we critically appraise the current controversy in the literature considering the fate of the aortic root, discussing the aforementioned root interventions for which provides better outcomes for mortality and risk of re-intervention. Literature search was performed using electronic database through PubMed, Google scholar, and Embase focussing on studies reporting outcomes and re-intervention rates for these approaches. Limited by the heterogeneity in surgical strategy, with most studies being single-centred retrospective experiences, further fuel this ongoing debate. The literature reveals rather contrasting results whilst comparing root-sparing repair, versus the extensive root replacement; whilst some studies report no statistically significant difference, others show one superior over the other. There is greater consensus when considering risk of re-operation, with studies showing higher rates of re-operation in root-sparing group compared to replacement; however, many others show no statistically significant difference. In conclusion, the conflicting outcomes reported in the literature, with their inherent limitations, results in the current inability to reach a definitive answer. There remains support in the current literature for both approaches with much of the decision-making being surgeon-bound with many significant influencing factors on a case-by-case basis.
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Tarkas et al. (2021) conducted a review in Acute type A aortic dissection. Aortic root-sparing repair vs. Aortic root replacement was evaluated on Mortality and risk of re-intervention. Aortic root-sparing repair compared to root replacement yielded conflicting outcomes for mortality and re-intervention, with current literature unable to definitively support one approach.
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