March 1, 1995Journal of the American Society of Nephrology
How should renal hemodynamic data be indexed in obesity?
Why the study?
Does indexing renal plasma flow to height rather than body surface area provide more accurate values in obese subjects?
Population
215 subjects varying in age, gender, height, weight, obesity, and mean arterial blood pressure.
Comparison
Indexing renal plasma flow (RPF) to height vs Indexing renal plasma flow to body surface area
Design
Cross-sectional
Authors
Discussion
Loading...
Member takes
Implication
Height-based RPF indexing may avoid artifactual declines in obesity; leaves open whether it improves clinical or research standards over BSA.
Structured PICO
Does indexing renal plasma flow to height rather than body surface area provide more accurate values in obese subjects?
P
Population
215 subjects varying in age, gender, height, weight, obesity, and mean arterial blood pressure (55 normotensive, 160 hypertensive).
I
Intervention
Indexing renal plasma flow (RPF) to height
C
Comparator
Indexing renal plasma flow (RPF) to body surface area (1.73 m2)
O
Outcome
Renal plasma flow (RPF) determined by measuring the clearance of (131I)para-aminohippuric acidsurrogate
Indexing renal plasma flow to height rather than body surface area prevents the calculation of inappropriately low RPF values in obese patients.
Cite This Study
Schmieder et al. (1995) studied this question.