Population
Rat myocardium (papillary muscles)
Comparison
Tetanic contractions elicited by suprathreshold… vs Twitch tension under steady-state stimulation in…
Design
Preclinical
Authors
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Offers experimental utility for studying contractility independent of SR function; leaves open clinical translation pending in vivo studies.
Tetanic contractures in caffeine-treated rat myocardium represent a useful tool to investigate the contractile response of intact myocardial preparations with a nonfunctional sarcoplasmic reticulum.
Leite et al. (1995) studied this question.
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