Key result
Early treatment with Gemfibrozil in two young siblings with familial hyperchylomicronemia showed no side effects and significantly reduced the risk of acute pancreatitis.
Why the study?
Does gemfibrozil reduce the risk of acute pancreatitis and is it safe in very young children with familial hyperchylomicronemia?
Case Report (n=2)
Does gemfibrozil reduce the risk of acute pancreatitis and is it safe in very young children with familial hyperchylomicronemia?
Early treatment with gemfibrozil appears safe and effective in reducing the risk of acute pancreatitis in very young children with familial hyperchylomicronemia.
No takes yet. Share an insight, caveat, or question.
Supports gemfibrozil investigation in pediatric familial hyperchylomicronemia; hypothesis-generating and should not yet change practice.
Azkawi et al. (2010) conducted a case report in Familial hyperchylomicronemia (n=2). Gemfibrozil was evaluated on Safety and risk of acute pancreatitis. Early treatment with Gemfibrozil in two young siblings with familial hyperchylomicronemia showed no side effects and significantly reduced the risk of acute pancreatitis.
Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context: