Key result
VA-ECMO plus IABP was associated with lower in-hospital mortality compared to VA-ECMO alone (OR 0.52; 95% CI 0.21-1.31) or IABP alone (OR 0.20; 95% CI 0.08-0.55) in AMICS patients.
Why the study?
The effectiveness of concomitant intra-aortic balloon pump with veno-arterial extracorporeal membrane oxygenation in patients with acute myocardial infarction with cardiogenic shock is contested in the literature.
Does VA-ECMO plus IABP reduce in-hospital all-cause mortality in patients with acute myocardial infarction with cardiogenic shock compared to VA-ECMO alone or IABP alone?
Population
AMICS patients including 3,580 receiving VA-ECMO with IABP
Comparison
VA-ECMO plus IABP vs IABP alone and vs VA-ECMO alone
Design
Meta-analysis
Follow-up
30-days
Authors
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Concomitant IABP with VA-ECMO was associated with lower short-term mortality in AMICS; leaves open effects on weaning and need for prospective confirmation.
Meta-Analysis (n=4,686)
Does VA-ECMO plus IABP reduce in-hospital all-cause mortality in patients with acute myocardial infarction with cardiogenic shock compared to VA-ECMO alone or IABP alone?
Odds Ratio: 0.52 (95% CI 0.21–1.31)
Concomitant use of VA-ECMO and IABP in AMICS patients is associated with reduced in-hospital and 30-day mortality and higher rates of weaning from VA-ECMO compared to either therapy alone.
Liu et al. (2023) conducted a meta-analysis in Acute myocardial infarction with cardiogenic shock (AMICS) (n=4,686). VA-ECMO plus IABP vs. VA-ECMO alone or IABP alone was evaluated on In-hospital all-cause mortality (OR 0.52, 95% CI 0.21-1.31). VA-ECMO plus IABP was associated with lower in-hospital mortality compared to VA-ECMO alone (OR 0.52; 95% CI 0.21-1.31) or IABP alone (OR 0.20; 95% CI 0.08-0.55) in AMICS patients.
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