Key result
Primary percutaneous coronary intervention within 90 minutes of initial assessment is associated with better short-term and long-term clinical outcomes, including lower mortality, in patients with acute myocardial infarction.
Why the study?
Does a door-to-balloon time of less than 90 minutes improve clinical outcomes in patients with acute myocardial infarction undergoing primary percutaneous coronary intervention?
Systematic Review
Does a door-to-balloon time of less than 90 minutes improve clinical outcomes in patients with acute myocardial infarction undergoing primary percutaneous coronary intervention?
Achieving a door-to-balloon time of less than 90 minutes for primary PCI in STEMI patients is crucial for improving short- and long-term clinical outcomes.
Shorter diagnosis-to-angioplasty times improve AMI outcomes; reinforces consensus on minimizing reperfusion delays.
OBJECTIVES: To explore the relationship between time of initial diagnosis of acute myocardial infarction to primary angioplasty on patient’s outcome. MATERIAL AND METHODS: A systematic review of published articles in international databases (CENTRAL, SCOPUS and MEDLINE). A time limited criterion was applied related to the articles publication (articles published between 2012 and 2016). Seventeen articles were found that met the criteria for participation in the review. RESULTS: According to the results, the majority of studies showed that time to treatment (primary angioplasty) was less than 90 minutes from the initial assessment, resulting in better outcomes of patients. The time from patient presentation to hospital in ST segment elevetion myocardial infarction (STEMI) diagnosis and laboratory activation for catheterization is a powerful guide to the total time from admittance to primary percutaneous coronary intervention (PPCI). In some of the stydies were described the effect of time from assessment on initiation of angioplasty in patients short-term or long-term outcomes and in others were investigated the reasons of delay until the onset of primary angioplasty. Endly in some were found time reduction practices from assessment to the onset of angioplasty and improving the clinical outcome. CONCLUSION: Early treatment is important for the best clinical outcomes of patients with acute myocardial infarction (AMI) and seems to be feasible.
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Saita et al. (2018) conducted a systematic review in Acute myocardial infarction (STEMI). Door-to-balloon time < 90 minutes vs. Door-to-balloon time > 90 minutes was evaluated on Clinical outcomes (including mortality and complications). Primary percutaneous coronary intervention within 90 minutes of initial assessment is associated with better short-term and long-term clinical outcomes, including lower mortality, in patients with acute myocardial infarction.
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