Key result
This review highlights the complex lipid biology of the transition dairy cow, detailing how fatty acids and lipid mediators influence metabolic stress, insulin resistance, and fatty liver disease.
Why the study?
Inability of periparturient dairy cows to adapt to lactation can cause metabolic stress, lipotoxicity, fatty liver disease, and ketosis.
Population
Periparturient dairy cows
Design
Review
Authors
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Uncontrolled lipolysis risks lipotoxicity in transition cows; leaves open translation to human cardiometabolic models.
This review summarizes contemporary perspectives on lipid metabolism and fatty acid signaling in transition dairy cows, highlighting mechanisms of metabolic stress and fatty liver disease.
Joseph W. McFadden (2020) conducted a review in Metabolic stress, fatty liver disease, and ketosis in periparturient dairy cows. This review highlights the complex lipid biology of the transition dairy cow, detailing how fatty acids and lipid mediators influence metabolic stress, insulin resistance, and fatty liver disease.
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