What question did this study set out to answer?

To examine secular changes in the incidence, underlying causes, and case mortality of acute pancreatitis over an 11-year period.

July 1, 1985GutOpen Access

Acute pancreatitis: a lethal disease of increasing incidence.

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Authors

ACAnthony P. CorfieldUniversity of Nottingham MCM J CooperRoyal Devon & Exeter NHS Foundation Trust RWR C N WilliamsonRoyal Society of Medicine

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Implication

Epidemiological study finds rising incidence and high mortality in acute pancreatitis patients, highlighting neglected gallstones as a primary cause of recurrent attacks.

Key Points

To examine secular changes in the incidence, underlying causes, and case mortality of acute pancreatitis over an 11-year period.
Retrospective population-based study of 650 patients presenting with 737 attacks of acute pancreatitis between 1968 and 1979 in the Bristol clinical area.
Evaluation of demographic profiles, annual incidence rates compared to the previous decade, clinical outcomes, post-mortem findings, and recurrent episodes.
Annual incidence of first attacks rose from 53.8 to 73.0 cases per million population compared to the preceding decade, while case mortality remained unchanged at 20%.
Gall stones were identified in 50% of first attacks and 51% of recurrences, while alcohol-associated cases comprised 8% overall after a three-fold rise.
Diagnosis occurred at necropsy in 35% of fatal cases, and 80 patients suffered 99 recurrent attacks with a 12% mortality rate.

Cite This Study

Corfield et al. (1985) studied this question.

synapsesocial.com/papers/6a79f9c2fb5b6b43000dde04 https://doi.org/10.1136/gut.26.7.724

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Implication

Epidemiological study finds rising incidence and high mortality in acute pancreatitis patients, highlighting neglected gallstones as a primary cause of recurrent attacks.

Acute pancreatitis: a lethal disease of increasing incidence.

Discussion

Member takes

Implication

Key Points

Cite This Study

Acute pancreatitis: a lethal disease of increasing incidence.

Discussion

Member takes

Implication

Key Points

Cite This Study

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