Why the study?
Does intermittent subcutaneous heparin reduce cardiovascular death in patients with previous myocardial infarction?
Population
222 patients with known previous myocardial infarction
Comparison
Heparin 200 mg subcutaneously twice weekly vs Saline placebos
Design
Other, placebo-controlled
Follow-up
2 years
Authors
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May support heparin consideration post-MI; hypothesis-generating and should not yet change practice pending randomized confirmation.
Does intermittent subcutaneous heparin reduce cardiovascular death in patients with previous myocardial infarction?
Intermittent subcutaneous heparin significantly reduced cardiovascular death over two years in patients with prior myocardial infarction.
Engelberg et al. (1956) studied this question.
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