Key result
In a computational model, increasing stenotic severity and artery stiffness increased flow velocity, wall shear stress, and pressure difference, with elliptical shapes most prone to plaque formation.
Computational fluid dynamics modeling reveals that elliptical stenotic shapes and increased arterial stiffness significantly worsen hemodynamic profiles, potentially accelerating plaque progression.
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Stenotic severity raises modeled velocity, shear, and pressure drop; leaves open clinical translation pending validation.
Pabi et al. (2023) studied Stenosed artery. Stenotic shapes, degrees of stenosis, and arterial wall stiffnesses was evaluated on Hemodynamics (velocity profile, pressure, wall shear stress, wall deformation, oscillatory shear index). In a computational model, increasing stenotic severity and artery stiffness increased flow velocity, wall shear stress, and pressure difference, with elliptical shapes most prone to plaque formation.