Why the study?
Does a positive exercise ECG predict future myocardial infarction and coronary heart disease?
Does a positive exercise ECG predict future myocardial infarction and coronary heart disease?
A positive exercise ECG is associated with a significantly increased risk of future myocardial infarction and coronary heart disease over an 11-year follow-up period.
Positive exercise ECG may flag higher long-term risk; leaves open its added value for risk stratification.
Sixty patients, 30 with ST segment changes in the exercise ECG in 1956 (probands) and 30 without such changes (partners) were carefully examined in 1967. There were 4 deaths from myocardial infarction in the proband group and none among the partners. The probability of myocardial infection in the 11-year period was 3 times greater for the persons with a positive exercise test than with a negative one. A history of coronary heart disease and a positive ECG in 1967 were recorded for 15 probands while 5 of the partners had CHD (p< 0.05).
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Åstrand et al. (1968) studied this question.
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