Key result
In patients with acute ischemic stroke, carotid artery stenosis was significantly associated with a higher prevalence of diabetes mellitus compared to those without stenosis (41.8% vs 16.4%; OR 3.674).
Why the study?
The study was conducted to determine the association of carotid artery stenosis with diabetes mellitus in patients presenting with acute ischemic stroke.
Is carotid artery stenosis associated with diabetes mellitus in patients with acute ischemic stroke?
Case-Control (n=220)
No
Is carotid artery stenosis associated with diabetes mellitus in patients with acute ischemic stroke?
Odds Ratio: 3.674 (95% CI 1.95–6.91)
Absolute Event Rate: 41.8% vs 16.4%
p-value: p=0.0001
Diabetes mellitus is significantly associated with the presence of carotid artery stenosis in patients presenting with acute ischemic stroke.
Supports targeted evaluation in diabetic stroke patients; hypothesis-generating and requires prospective confirmation before practice change.
Objective: To determine the association of carotid artery stenosis with diabetes mellitus in patients of acute ischemic stroke Study Setting: The study was conducted in Allama Iqbal Memorial Teaching Hospital, Sialkot. Duration of Study: April 13, 2018 to October 13, 2018 Study Design: Case-Control Study Subjects & Methods: A total 220 (110 cases/ 110 controls) patients fulfilling selection criteria were enrolled from emergency of Department of Medicine, Allama Iqbal Memorial Teaching Hospital, Sialkot. Blood drop was obtained from each patient by pricking in index finger and using glucometer and lentils. Reading of glucometer was obtained. If BSR was >186mg/dl and patient had history of DM, then DM was labeled. Data were entered and analyzed in SPSS v25.0. Results: Total 220 (110 cases/ 110 controls) patients were selected for this study. Among cases, mean age was 54.7±9.1 years and 55.1±8.8 years among controls. Among cases, there were 67(60.9%) males and 43(39.1%) females, while 75(68.2%) males and 35(31.8%) females among controls. By comparing diabetes mellitus between groups, it was found that percentage of DM was 41.8% with carotid artery stenosis and 16.4% without carotid artery stenosis. The difference was significant (p=0.0001). Conclusion: There is an association of carotid artery stenosis with diabetes mellitus in patients of acute ischemic stroke. Patients with carotid artery stenosis have significant chances to have diabetes mellitus.
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Kosar et al. (2021) conducted a case-control in Acute Ischemic Stroke (n=220). Carotid artery stenosis vs. No carotid artery stenosis was evaluated on Prevalence of Diabetes Mellitus (OR 3.674, 95% CI 1.95-6.91, p=0.0001). In patients with acute ischemic stroke, carotid artery stenosis was significantly associated with a higher prevalence of diabetes mellitus compared to those without stenosis (41.8% vs 16.4%; OR 3.674).
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