Modular synthesis framework for combined separation/reaction systems

As an extension to our earlier work (1999a), this article presents a systematic approach for the synthesis of combined separation/reaction systems which involves a phenomena‐based representation formulated within a superstructure optimization framework. A multifunctional, mass‐/heat‐transfer‐based process module is utilized as the building block of process alternatives. Within this module, Gibbs‐free‐energy‐based “driving‐force” constraints are introduced to describe the physiochemical phenomena and to ensure feasibility of pure separation, reaction or combined separation/reaction (such as reactive distillation). A superstructure of these multipurpose modules is then systematically constructed to represent process alternatives, which are not explicitly prepostulated, but investigated, as mass and heat exchange network possibilities.