Key result
Elderly status (age > 65 years) was independently associated with a significantly increased risk of all-cause mortality after heart failure hospitalization compared to non-elderly patients (HR 1.47).
Why the study?
Heart failure mortality had not been clearly compared between elderly and non-elderly Thai patients.
Does elderly status increase the risk of mortality in Thai patients hospitalized for heart failure?
Observational (n=201,709)
Does elderly status increase the risk of mortality in Thai patients hospitalized for heart failure?
Elderly status is a strong independent predictor of mortality after heart failure hospitalization in Thai patients, highlighting the need for improved quality of care and follow-up in this vulnerable population.
Answers are grounded in this paper and cite their sources.
Elderly Thai HF patients had higher mortality; observational data leaves open whether age-specific strategies improve outcomes.
OBJECTIVE: To investigate heart failure mortality compared between elderly and non-elderly Thai patients. METHODS: This study included patients at least 18 years of age who were admitted to the hospital with a primary diagnosis of heart failure (ICD-10-TM code: 150.9) during 2008-2012 according to three major Thailand reimbursement systems (civil servant, social security, and universal coverage systems). Patients were categorized into either the elderly group (age > 65 years) or the non-elderly group (age ≤ 65 years). Mortality rate and survival analysis were compared between groups. Demographic, underlying disease and comorbid condition data were collected. Cardiovascular and non-cardiovascular death was also analyzed. After adjusting for potential confounders, elderly status remained the second strongest factor associated with increased risk of mortality after heart failure hospitalization following chronic kidney disease. CONCLUSIONS: The overall mortality rate after heart failure hospitalization was a very high 50.8%. Multivariate analysis revealed elderly status to be an independent predictor of mortality after hospitalization. This finding suggests that improvements are needed related to the quality of care and follow-up given to elderly Thai heart failure patients.
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Krittayaphong et al. (2018) conducted an observational in Heart failure (n=201,709). Elderly status (age > 65 years) vs. Non-elderly status (age ≤ 65 years) was evaluated on All-cause mortality (HR 1.47, 95% CI 1.46-1.49, p=<0.001). Elderly status (age > 65 years) was independently associated with a significantly increased risk of all-cause mortality after heart failure hospitalization compared to non-elderly patients (HR 1.47).
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