December 26, 2007European Journal of Heart Failure
Long-Term Survival in Patients Older than 80 Years Hospitalised for Heart Failure. A 5-Year Prospective Study
Key result
In heart failure patients older than 80 years, 5-year survival was 19% (vs 48% in matched general population), and reduced ejection fraction strongly predicted death (HR 1.72; 95% CI 1.24-2.37).
Population
799 consecutive patients hospitalized for a first heart failure episode, focusing on the 305 patients aged…
Design
Cohort
Follow-up
5 years
Authors
Discussion
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Implication
Marks elderly HF as high-risk with poor longevity; leaves open whether therapy optimization improves outcomes in this group.
Key Points
- This study aims to assess the clinical characteristics and long-term prognosis of heart failure in patients over 80 years old.
- Prospective inclusion of hospitalized patients with first heart failure episode in Somme, France, in 2000
- Assessment of clinical features, treatment prescribed, and survival outcomes
- Analysis of mortality predictors through multivariable methods
- 5-year survival rate for elderly patients was 19%, compared to 48% in the age- and sex-matched general population
- Over 60% of deaths were attributed to cardiovascular causes
- Reduced ejection fraction significantly predicted mortality (HR 1.72, 95% CI 1.24-2.37, p=0.001)
Study Design
Type
Cohort (n=799)
Structured PICO
P
Population
799 consecutive patients hospitalized for a first heart failure episode, focusing on the 305 patients (38%) aged over 80 years.
C
Comparator
Age- and sex-matched general population
O
Outcome
5-year survivalhard clinical
Main Result
Absolute Event Rate: 19% vs 48%
Heart failure patients older than 80 years have a very poor 5-year survival (19%) compared to the general population, and life-saving drugs are largely underused in this group.
Cite This Study
Mahjoub et al. (2007) conducted a cohort in Heart Failure (n=799). In heart failure patients older than 80 years, 5-year survival was 19% (vs 48% in matched general population), and reduced ejection fraction strongly predicted death (HR 1.72; 95% CI 1.24-2.37).