Key result
Abnormal heart rate recovery is independently associated with higher pre-exercise (r=-0.36, p=0.004) and post-exercise BNP levels in patients with chest discomfort and normal systolic function.
Why the study?
Does abnormal heart rate recovery associate with elevated brain natriuretic peptide levels in patients with chest discomfort and normal systolic function?
Population
105 patients with chest pain and normal systolic function, without respiratory difficulty, pulmonary…
Comparison
Abnormal heart rate recovery defined as ≤24… vs Normal heart rate recovery
Design
Cross-sectional
Authors
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Heart rate recovery assessment should not change practice yet; leaves open whether it identifies subclinical strain beyond BNP in chest discomfort.
Cross-Sectional (n=105)
No
Does abnormal heart rate recovery associate with elevated brain natriuretic peptide levels in patients with chest discomfort and normal systolic function?
Effect estimate: r=-0.36
Absolute Event Rate: 51% vs 18.2%
p-value: p=0.004
In patients with chest discomfort and normal systolic function, delayed heart rate recovery after exercise is independently associated with higher pre- and post-exercise BNP levels, suggesting a link between autonomic dysfunction and early cardiac strain.
Lee et al. (2010) conducted a cross-sectional in Chest discomfort with normal systolic function (n=105). Abnormal heart rate recovery (≤24 beats per 2 minutes) vs. Normal heart rate recovery (>24 beats per 2 minutes) was evaluated on Correlation between heart rate recovery and pre-exercise brain natriuretic peptide (BNP) level (r=-0.36, p=0.004). Abnormal heart rate recovery is independently associated with higher pre-exercise (r=-0.36, p=0.004) and post-exercise BNP levels in patients with chest discomfort and normal systolic function.
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