Key result
Higher Life's Crucial 9 scores were significantly associated with a lower prevalence of metabolic syndrome, with each one-unit increase in score reducing the odds of metabolic syndrome by 5.9% (OR 0.941).
Why the study?
Metabolic Syndrome is closely linked to cardiovascular disease, but no studies have examined the relationship between Life's Crucial 9 and MetS.
Does a higher Life's Crucial 9 (LC9) score reduce the odds of metabolic syndrome in U.S. adults?
Population
28,555 U.S. adults
Comparison
Life's Crucial 9, health behavior score, and health factors score associations with MetS
Design
Cross-sectional study
Authors
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LC9 was associated with MetS; hypothesis-generating and requires prospective validation before any practice change.
Cross-Sectional (n=28,555)
Does a higher Life's Crucial 9 (LC9) score reduce the odds of metabolic syndrome in U.S. adults?
Odds Ratio: 0.941 (95% CI 0.939–0.944)
p-value: p=<0.0001
Higher Life's Crucial 9 scores are associated with a lower prevalence of metabolic syndrome in U.S. adults, exhibiting a curvilinear relationship with a more pronounced protective effect above a score of 70.56.
Wang et al. (2025) conducted a cross-sectional in Metabolic Syndrome (MetS) (n=28,555). Life's Crucial 9 (LC9) score vs. Lower LC9 score was evaluated on Metabolic Syndrome (OR 0.941, 95% CI 0.939-0.944, p=<0.0001). Higher Life's Crucial 9 scores were significantly associated with a lower prevalence of metabolic syndrome, with each one-unit increase in score reducing the odds of metabolic syndrome by 5.9% (OR 0.941).
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