Key result
A case presentation of a 58-year-old woman with minimal platelet response to clopidogrel after PCI highlights a clinician update discussing strategies for the prevention of stent thrombosis.
Case Report (n=1)
A clinician update discussing strategies to prevent stent thrombosis, emphasizing the potential role of platelet reactivity testing in patients undergoing PCI.
Supports individualized antiplatelet strategies in clopidogrel nonresponders post-PCI; leaves open whether reactivity testing reduces stent thrombosis.
Case Presentation—A 58-year-olddiabetic woman with stable an-gina pectoris (class II symptoms de-spite medical therapy) presented for elective cardiac catheterization after undergoing a stress test that demon-strated anterior wall ischemia at a low-moderate workload. Coronary angiog-raphy demonstrated single-vessel disease with a 90 % lesion in the left anterior descending (LAD) coronary artery (Figure, A). Treatment with per-cutaneous coronary intervention (PCI) was selected as a revascularization strategy, and a drug-eluting stent (DES) was deployed in the LAD with-out complications (Figure, B). Before discharge, a treating physician con-cerned about the risk for stent throm-bosis assessed the patient’s platelet reactivity using point-of-care testing, which demonstrated minimal platelet response to clopidogrel. This clinician update will discuss strategies for the prevention of stent thrombosis.
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Kirtane et al. (2011) conducted a case report in Stable angina pectoris (n=1). Strategies for the prevention of stent thrombosis was evaluated. A case presentation of a 58-year-old woman with minimal platelet response to clopidogrel after PCI highlights a clinician update discussing strategies for the prevention of stent thrombosis.
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