Key result
Major depressive disorder had a point prevalence of 23% among patients hospitalized with acute coronary syndrome, and was significantly associated with female gender, age ≤ 60, and prior MDD history.
Why the study?
What is the prevalence of Major Depressive Disorder and its associated factors in patients hospitalized with Acute Coronary Syndrome?
Cross-Sectional (n=356)
Yes
What is the prevalence of Major Depressive Disorder and its associated factors in patients hospitalized with Acute Coronary Syndrome?
Major Depressive Disorder is highly prevalent (23%) in patients hospitalized with Acute Coronary Syndrome, highlighting the need for targeted screening, particularly in younger women with a history of MDD and a sedentary lifestyle.
BACKGROUND: Major Depressive Disorder (MDD) is one of the most common mental illnesses in psychiatry, being considered a risk factor for Acute Coronary Syndrome (ACS). OBJECTIVE: To assess the prevalence of MDD in ACS patients, as well as to analyze associated factors through the interdependence of sociodemographic, lifestyle and clinical variables. METHODS: Observational, descriptive, cross-sectional, case-series study conducted on patients hospitalized consecutively at the coronary units of three public hospitals in the city of Rio de Janeiro over a 24-month period. All participants answered a standardized questionnaire requesting sociodemographic, lifestyle and clinical data, as well as a structured diagnostic interview for the DSM-IV regarding ongoing major depressive episodes. A general log-linear model of multivariate analysis was employed to assess association and interdependence with a significance level of 5%. RESULTS: Analysis of 356 patients (229 men), with an average and median age of 60 years (SD ± 11.42, 27-89). We found an MDD point prevalence of 23%, and a significant association between MDD and gender, marital status, sedentary lifestyle, Killip classification, and MDD history. Controlling for gender, we found a statistically significant association between MDD and gender, age ≤ 60 years, sedentary lifestyle and MDD history. The log-linear model identified the variables MDD history, gender, sedentary lifestyle, and age ≤ 60 years as having the greatest association with MDD. CONCLUSION: Distinct approaches are required to diagnose and treat MDD in young women with ACS, history of MDD, sedentary lifestyle, and who are not in stable relationships.
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Figueiredo et al. (2017) conducted a cross-sectional in Acute Coronary Syndrome (n=356). Sociodemographic, lifestyle and clinical risk factors was evaluated on Point prevalence of Major Depressive Disorder (MDD). Major depressive disorder had a point prevalence of 23% among patients hospitalized with acute coronary syndrome, and was significantly associated with female gender, age ≤ 60, and prior MDD history.
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