Depressive Symptom Dimensions and Cardiovascular Prognosis Among Women With Suspected Myocardial Ischemia
Key result
Somatic depressive symptoms were associated with an increased risk of cardiovascular-related mortality and events (HR 1.63; 95% CI 1.28-2.08) among women with suspected myocardial ischemia.
Why the study?
Do specific dimensions of depressive symptoms predict cardiovascular-related mortality and events in women with suspected myocardial ischemia?
Population
550 women with suspected myocardial ischemia referred for coronary angiography to evaluate chest pain or…
Design
Cohort
Follow-up
median 5.8 years
Authors
Discussion
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Member takes
Implication
May support targeted somatic symptom assessment in women evaluated for ischemia; leaves open causal effects and intervention benefits.
Study Design
Type
Cohort (n=550)
Multicenter
Yes
Structured PICO
Do specific dimensions of depressive symptoms predict cardiovascular-related mortality and events in women with suspected myocardial ischemia?
P
Population
550 women with suspected myocardial ischemia referred for coronary angiography, followed for a median of 5.8 years.
E
Exposure
Somatic and appetitive depressive symptom dimensions assessed via the Beck Depression Inventory
O
Outcome
Cardiovascular-related mortality and events (stroke, myocardial infarction, and congestive heart failure)composite
Main Result
Hazard Ratio: 1.63 (95% CI 1.28–2.08)
In women with suspected myocardial ischemia, somatic but not cognitive/affective depressive symptoms are associated with an increased risk of cardiovascular events and mortality.
Cite This Study
Linke et al. (2009) conducted a cohort in suspected myocardial ischemia (n=550). Somatic depressive symptoms was evaluated on Cardiovascular-related mortality and events (stroke, myocardial infarction, and congestive heart failure) (HR 1.63, 95% CI 1.28-2.08). Somatic depressive symptoms were associated with an increased risk of cardiovascular-related mortality and events (HR 1.63; 95% CI 1.28-2.08) among women with suspected myocardial ischemia.