aDepartment of Pharmacology and Toxicology, University of Louisville School of Medicine, Louisville, Kentucky, USA, bGenetics and Genomic Biology Program, Research Institute, The Hospital for Sick Children, Toronto, Ontario, Canada and cDepartment of Pharmacology, University of Oxford, Oxford, UK Received and accepted 27 September 1999 Correspondence to David W. Hein, Department of Pharmacology and Toxicology, University of Louisville School of Medicine, Louisville, Kentucky 40292, USA
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