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A general method providing access to stabilized azomethine ylides generated from substituted 1,3-and 3,1-aryloxazines was developed.A two-step sequence based on 1,3-dipolar cycloaddition reactions with N-arylmaleimides was elaborated to give a series of highly substituted pyrrolopyrrolidines in good yields.
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Husson et al. (2002) studied this question.
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