Key result
Use of ischemic heart disease (IHD) terminology for women with MINOCA/INOCA facilitates recognition of elevated cardiovascular risk and provides potential treatment targets.
Using ischemic heart disease terminology instead of focusing solely on obstructive atherosclerosis improves the recognition and management of cardiovascular risk in women with MINOCA/INOCA.
May warrant CMD evaluation in MINOCA/INOCA; leaves open targeted therapies to reduce events and HFpEF.
The syndromes of myocardial infarction/myocardial ischemia with No Obstructive Coronary Artery Disease (MINOCA/INOCA) are increasingly evident. A majority of these patients have coronary microvascular dysfunction. These patients have elevated risk for a cardiovascular event (including acute coronary syndrome, myocardial infarction, stroke, and repeated cardiovascular procedures) and appear to be at higher risk for development of heart failure with preserved ejection fraction. Terminology such as coronary artery disease or coronary heart disease is often synonymous with obstructive atherosclerosis in the clinician's mind, leaving one at a loss to recognize or explain the phenomenon of MINOCA and INOCA with elevated risk. We review the available literature regarding stable and unstable ischemic heart disease that suggests that use of the ischemic heart disease (IHD) terminology matters for women, and should facilitate recognition of risk to provide potential treatment targets and optimized health.
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Pacheco et al. (2018) conducted a review in MINOCA/INOCA (myocardial infarction/ischemia and no obstructive coronary artery disease). Ischemic heart disease (IHD) terminology was evaluated. Use of ischemic heart disease (IHD) terminology for women with MINOCA/INOCA facilitates recognition of elevated cardiovascular risk and provides potential treatment targets.
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