Why the study?
Despite treatment according to current recommendations, the long-term outcome remains severe in patients experiencing infectious complications after procedures.
What is the prognosis and mortality risk in patients undergoing lead extraction for infectious complications?
What is the prognosis and mortality risk in patients undergoing lead extraction for infectious complications?
Answers are grounded in this paper and cite their sources.
Despite treatment according to current recommendations, long-term mortality after lead extraction for infectious complications remains high, with 3-year mortality reaching up to 53%.
<ns3:p>In last years significantly higher rate of infectious complications than increase of procedure number has been observed. Despite treatment according to current recommendations in this group of patients long term outcome is still severe. Hospital mortality is around 5%, one year 7-37% and 3-year – even 53%. High risk of death belongs to patients with lead vegetations, lower to those with bacteriaemia and the lowest – when infection is localized to pocket. Risk of death beside type of infectious complication is increased by: dementia, heart failure, chronic kidney disease, anticoagulation treatment, bleeding which required blood transfusion and concomitant infection. Presence of tubular, free masses in echocardiography after extraction procedure also influence outcome. Patients with infectious complication require aggressive therapeutic options.</ns3:p>
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Mitkowski et al. (2019) studied this question.
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