May 28, 2021Open Access

The impact of post-operative atrial fibrillation on outcomes in coronary artery bypass graft and combined procedures.

View Full Paper

Ask AI

Bookmark

Why the study?

Post-operative atrial fibrillation is a common yet understudied issue after CABG that leads to higher mortality and stroke.

Does post-operative atrial fibrillation increase the risk of adverse outcomes in patients treated with CABG or combined procedures?

Structured PICO

Does post-operative atrial fibrillation increase the risk of adverse outcomes in patients treated with CABG or combined procedures?

Population

Patients treated with coronary artery bypass graft (CABG) or combined procedures

Intervention

Post-operative atrial fibrillation (POAF)

Comparator

No post-operative atrial fibrillation

Outcome

All-cause mortality, cardiac death, cerebral vascular accident (CVA), myocardial infarction (MI), repeated revascularization, major adverse cardiac event (MACE), and major adverse cardiac and cerebrovascular events (MACCEs)hard clinical

Post-operative atrial fibrillation following CABG or combined procedures is associated with increased all-cause mortality and stroke, emphasizing the need for close monitoring and judicious treatment.

Limitations

Heterogeneity among included studies

Implication

POAF after CABG raises mortality and stroke risk; reinforces perioperative monitoring and prevention while guiding targeted trials.

Abstract

BACKGROUND: Post-operative atrial fibrillation (POAF) is a common yet understudied clinical issue after coronary artery bypass graft (CABG) leading to higher mortality rates and stroke. This systematic review and meta-analysis evaluated the rates of adverse outcomes between patients with and without POAF in patients treated with CABG or combined procedures. METHODS: no new onset AF before or after revascularization. The outcomes assessed included all-cause mortality, cardiac death, cerebral vascular accident (CVA), myocardial infarction (MI), repeated revascularization, major adverse cardiac event (MACE), and major adverse cardiac and cerebrovascular events (MACCEs). RESULTS: = 62%). CONCLUSIONS: Patients with POAF after CABG or combined procedures are at an increased risk of all-cause mortality or CVAs. Therefore, POAF after such procedures should be closely monitored and treated judiciously to minimize risk of further complications. While there are studies on POAF versus no POAF on outcomes, the heterogeneity suggests that further studies are needed.