Why the study?
Does the onset time of malignant hyperthermia differ among various anesthetic drugs?
Population
477 cases of possible or fulminant malignant hyperthermia reported in the North American Malignant…
Comparison
Various anesthetic drugs vs Comparison among different anesthetic drugs
Design
Cohort
Authors
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May inform agent-specific MH vigilance; leaves open causal effects and practice changes pending prospective data.
Does the onset time of malignant hyperthermia differ among various anesthetic drugs?
The onset of malignant hyperthermia occurs later during desflurane and isoflurane anesthesia compared to sevoflurane or halothane, and has generally appeared later since 1998 due to decreased use of halothane and succinylcholine.
Visoiu et al. (2014) studied this question.
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