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Peptide B, the N‐terminal fragment of thioredoxin obtained by cyanogen bromide treatment was aminoethylated and digested with pepsin. Eight peptides were separated by high voltage paper electrophoresis and chromatography and characterized with respect to amino acid sequence. The results account for all 37 residues of peptide B. The N‐terminal sequence of peptide B was determined as: Ser‐Asp‐Lys‐Ile‐Ile‐His‐Leu‐Thr‐Asp‐Asp‐Ser‐Phe.
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Holmgren et al. (1968) studied this question.
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