Why the study?
Thrombotic complications in CMML patients are rarely reported due to frequent immune-mediated hemorrhagic diathesis, and the management of rare right atrial thrombi remains poorly known.
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Highlights the rare occurrence and management challenges of massive right atrial thrombosis in a patient with chronic myelomonocytic leukemia.
Chronic myelomonocytic leukemia (CMML) is a clonal hematopoietic stem cell disorder with overlapping myelodysplastic and myeloproliferative features. The disease is generally characterized by blood monocytosis, bone marrow dysplasia, cytopenia, and hepatosplenomegaly. While malignant blood diseases are frequently associated with a high risk of thromboembolism, CMML is often accompanied by immune-mediated hemorrhagic diathesis. Indeed, very few reports in literature report thrombotic complications of CMML patients. We will briefly present here the case of a patient with CMML who developed a massive right atrial thrombus. We aim to highlight the non-negligible thrombotic burden of the disease, and we will get through the differential diagnosis of right atrial masses and the management of right atrial thrombi, which are a rare and poorly known entity.
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Bergonti et al. (2021) studied this question.
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