Why the study?
High-sensitivity cardiac troponin assays allow earlier rule-out of myocardial infarction, but the efficacy and safety of this strategy remained uncertain in suspected acute coronary syndrome.
Does an early rule-out pathway using high-sensitivity cardiac troponin I <5 ng/L at presentation reduce length of stay without increasing 30-day myocardial infarction or cardiac death in patients with suspected acute coronary syndrome?
Does an early rule-out pathway using high-sensitivity cardiac troponin I <5 ng/L at presentation reduce length of stay without increasing 30-day myocardial infarction or cardiac death in patients with suspected acute coronary syndrome?
An early rule-out pathway for suspected ACS using high-sensitivity troponin I <5 ng/L at presentation significantly reduced length of stay and increased discharges without increasing cardiac events at 1 year.
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Supports earlier ED discharge in suspected ACS; extends RCT evidence for hs-cTn pathways despite non-inferiority not formally met.
Anand et al. (2020) studied this question.
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