What question did this study set out to answer?

Review the pathophysiology of cancer treatment-induced cardiovascular complications and outline current approaches for early detection, monitoring, and multidisciplinary clinical management.

May 28, 2025Middle Eastern Cancer and Oncology JournalOpen Access

Cardio-Oncology: Bridging the Gap Between Cardiovascular Health and Cancer Care

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Why the study?

There is an increasing prevalence of cardiotoxicity induced by chemotherapy, targeted therapy, immunotherapy, and radiotherapy in cancer patients.

Design

Review

Authors

HSHadi SkouriHeart Failure & Transplant

Discussion

Member takes

Implication

Supports multidisciplinary cardio-oncology care with advanced monitoring; leaves open need for RCTs to guide implementation.

Key Points

Review the pathophysiology of cancer treatment-induced cardiovascular complications and outline current approaches for early detection, monitoring, and multidisciplinary clinical management.
Narrative review examining cardiotoxicity across chemotherapy, targeted therapies, immunotherapy, and radiotherapy regimens.
Evaluation of diagnostic tools, including serum biomarkers (cardiac troponins and natriuretic peptides) and advanced imaging (cardiac MRI and speckle-tracking echocardiography).
Cancer therapies induce diverse cardiovascular sequelae, categorizing chemotherapy-related cardiac dysfunction into irreversible type I myocardial injury (such as anthracyclines) and reversible type II dysfunction (such as trastuzumab).
Radiation therapy promotes broad cardiovascular pathology, including coronary artery disease, valvular dysfunction, pericardial disease, and myocardial fibrosis.
Routine surveillance utilizing cardiac troponin, natriuretic peptides, and advanced strain echocardiography facilitates the early identification of subclinical cardiac dysfunction.

Structured PICO

Population

Cancer patients at risk for cardiovascular complications from cancer therapies

Intervention

Cardio-oncology multidisciplinary care, early screening, and monitoring (including biomarkers and advanced imaging)

Multidisciplinary collaboration and early screening with biomarkers and advanced imaging are critical to mitigate cardiovascular risks in cancer patients undergoing potentially cardiotoxic therapies.

Cite This Study

Hadi Skouri (2025) studied this question.

synapsesocial.com/papers/6a7aa8108a3ae1c74232e8db https://doi.org/10.61706/mecoj160134

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Cardio-Oncology: Bridging the Gap Between Cardiovascular Health and Cancer Care

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Cardio-Oncology: Bridging the Gap Between Cardiovascular Health and Cancer Care

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

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