Why the study?
Does exogenous norepinephrine induce an enhanced microproteinuric response in patients with insulin-dependent diabetes mellitus?
Population
24 subjects: 8 normoalbuminuric insulin-dependent diabetes mellitus patients, 8 microalbuminuric IDDM…
Comparison
Exogenous norepinephrine infusions at… vs Placebo infusion on separate days
Design
Other
Follow-up
Acute (during infusion)
Authors
Loading...
May exacerbate proteinuria with pressors in microalbuminuric IDDM; leaves open clinical relevance pending prospective validation.
Does exogenous norepinephrine induce an enhanced microproteinuric response in patients with insulin-dependent diabetes mellitus?
Exogenous norepinephrine acutely promotes glomerular protein leakage, with an enhanced response in microalbuminuric IDDM patients despite unaltered renal hemodynamic responsiveness.
Hoogenberg et al. (1998) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: