What is the clinical evidence from this study?

Study design: Observational. Population: End-stage renal disease (n=98). Intervention: Diabetic kidney disease vs. Nondiabetic kidney disease and healthy controls. Primary outcome: Peak systolic strain, peak diastolic strain, peak systolic strain rate, and peak diastolic strain rate of the radial artery (p=< 0.01).

What does this research mean for the field?

Radial artery elastic function measured by velocity vector imaging is significantly impaired in end-stage renal disease patients, with the greatest reduction observed in those with diabetic kidney disease compared to nondiabetic kidney disease and healthy controls. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

This study aims to evaluate radial artery elastic function changes in patients with end-stage renal disease using velocity vector imaging.

August 11, 2026The Journal of Vascular Access

A study on the utility of velocity vector imaging for assessment of radial artery elastic function in patients with end-stage renal disease

Q: What are the key findings of this study?

Velocity vector imaging parameters of radial artery elastic function were significantly lower in patients with diabetic kidney disease compared to nondiabetic kidney disease and healthy controls (p<0.01).

Q: What does this research mean for the field?

Radial artery elastic function measured by velocity vector imaging is significantly impaired in end-stage renal disease patients, with the greatest reduction observed in those with diabetic kidney disease compared to nondiabetic kidney disease and healthy controls. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

Q: What question did this study set out to answer?

This study aims to evaluate radial artery elastic function changes in patients with end-stage renal disease using velocity vector imaging.

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Key result

Velocity vector imaging shows lower radial artery elastic function in DKD versus NDKD and healthy controls.

P<0.01
n=98

Why the study?

This study aimed to assess changes in radial artery elastic function among patients with end-stage renal disease using velocity vector imaging.

Can velocity vector imaging (VVI) accurately assess changes in radial artery elastic function in patients with end-stage renal disease?

Population

68 pre-hemodialysis ESRD patients and 30 healthy individuals

Comparison

NDKD group vs DKD group vs healthy control group

Design

Retrospective analysis

Authors

GTGe TongCardiac Imaging YGYihua GaoCardiac Imaging KYKuichang YuanHeart Failure / Cardiomyopathy

Discussion

Member takes

Implication

VVI may detect radial artery changes in ESRD; leaves open its clinical utility for vascular access planning.

Key Points

This study aims to evaluate radial artery elastic function changes in patients with end-stage renal disease using velocity vector imaging.
Retrospective analysis of 68 pre-hemodialysis ESRD patients and 30 healthy individuals.
VVI analysis assessed peak systolic strain, peak diastolic strain, and their respective rates.
Receiver operating characteristic curve analysis was performed to evaluate VVI parameters' significance.
The DKD group demonstrated significantly lower Ss, SRs, Sd, and SRd compared to CG and NDKD groups (p < 0.01).
Statistically significant decreasing trends in VVI parameters were observed across CG, NDKD, and DKD groups (p trend < 0.001).
Area under the curve for VVI parameters ranged from 0.829 to 0.990, indicating high diagnostic accuracy.

Study Design

Type

Observational (n=98)

Multicenter

Structured PICO

Can velocity vector imaging (VVI) accurately assess changes in radial artery elastic function in patients with end-stage renal disease?

Population

98 participants, including 68 pre-hemodialysis ESRD patients and 30 healthy individuals, assessed for radial artery elastic function using velocity vector imaging.

Exposure

Velocity vector imaging (VVI) analysis of the long axis of the radial artery

Comparator

Healthy controls and comparison between NDKD and DKD groups

Outcome

Radial artery elastic function parameters: peak systolic strain (Ss), peak diastolic strain (Sd), peak systolic strain rate (SRs), and peak diastolic strain rate (SRd)surrogate

Main Result

p-value: p=< 0.01

Velocity vector imaging provides a novel and accurate method for quantifying radial artery elastic function and assessing arterial stiffness in patients with end-stage renal disease.

Cite This Study

Tong et al. (2026) conducted an observational in End-stage renal disease (n=98). Diabetic kidney disease vs. Nondiabetic kidney disease and healthy controls was evaluated on Peak systolic strain, peak diastolic strain, peak systolic strain rate, and peak diastolic strain rate of the radial artery (p=< 0.01). Velocity vector imaging parameters of radial artery elastic function were significantly lower in patients with diabetic kidney disease compared to nondiabetic kidney disease and healthy controls (p<0.01).

synapsesocial.com/papers/6a7ace3e3401087f2249e289 https://doi.org/10.1177/11297298261474550

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A study on the utility of velocity vector imaging for assessment of radial artery elastic function in patients with end-stage renal disease

Discussion

Member takes

Implication

Key Points

Study Design

Structured PICO

Main Result

Cite This Study

A study on the utility of velocity vector imaging for assessment of radial artery elastic function in patients with end-stage renal disease

Discussion

Member takes

Implication

Key Points

Study Design

Structured PICO

Main Result

Cite This Study

Also Consider

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