Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
January 1, 2011Archives of Medical ScienceOpen Access

Relationship between N-terminal pro-B-type natriuretic peptide levels and metabolic syndrome

View Full Paper
Ask AI
Bookmark
Share

Why the study?

Is metabolic syndrome associated with altered NT-proBNP levels in patients without heart failure?

Population

469 patients free of heart failure (230 with metabolic syndrome, 239 without metabolic syndrome)

Comparison

Metabolic syndrome and metabolic risk factors vs Absence of metabolic syndrome

Design

Cross-sectional

Authors

YBYuanyuan BaoChinese Academy of Medical Sciences & Peking Union Medical CollegeXSXiliang ShangFudan UniversityLZLinuo ZhouFudan University

Discussion

Loading...

Member takes

Implication

Lower NT-proBNP in metabolic syndrome warrants diagnostic caution; leaves open whether syndrome-specific cutoffs improve HF screening accuracy.

Structured PICO

Is metabolic syndrome associated with altered NT-proBNP levels in patients without heart failure?

P
Population
469 patients free of heart failure (230 with metabolic syndrome, 239 without metabolic syndrome)
I
Intervention
Metabolic syndrome and metabolic risk factors
C
Comparator
Absence of metabolic syndrome
O
Outcome
Plasma N-terminal pro-B-type natriuretic peptide (NT-proBNP) levelssurrogate

Metabolic syndrome and its components are associated with lower plasma NT-proBNP levels in patients without heart failure, suggesting NT-proBNP reduction may be a manifestation of metabolic syndrome.

Cite This Study

Bao et al. (2011) studied this question.

synapsesocial.com/papers/6a7ad2dd1ba4614d7ff40e12https://doi.org/10.5114/aoms.2011.22075
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1N-Terminal Pro Brain Natriuretic Peptide Is Inversely Related to Metabolic Cardiovascular Risk Factors and the Metabolic Syndrome2005 · 168 citations
  2. 2Influence of hypertension, left ventricular hypertrophy, and left ventricular systolic dysfunction on plasma N terminal proBNP2000 · 85 citations
  3. 3Plasma Brain Natriuretic Peptide Levels in Normotensive Noninsulin-Dependent Diabetic Patients with Microalbuminuria1999 · 65 citations
  4. 4Essential Biochemistry and Physiology of (NT-pro)BNP2004 · 572 citations
  5. 5An Unsuspected Metabolic Role for Atrial Natriuretic Peptides2005 · 112 citations