Key result
VSR repair was associated with lower 30-day mortality compared to no repair (51.7% vs 65.7%, P≤0.01), although overall VSR-AMI mortality remained high and unchanged between 1999 and 2014.
Why the study?
What are the trends in incidence, treatment, and mortality of VSR-AMI among Medicare beneficiaries, and does repair improve survival compared to no repair?
Cohort
Yes
What are the trends in incidence, treatment, and mortality of VSR-AMI among Medicare beneficiaries, and does repair improve survival compared to no repair?
Absolute Event Rate: 51.7% vs 65.7%
p-value: p=≤0.01
While the incidence of ventricular septal rupture complicating AMI has declined in the primary PCI era, mortality remains extremely high and overall repair rates have paradoxically decreased.
No takes yet. Share an insight, caveat, or question.
Persistent high VSR-AMI mortality unchanged despite primary PCI era; leaves open need for better therapies in prospective studies.
Goldsweig et al. (2018) conducted a cohort in Ventricular septal rupture complicating acute myocardial infarction. VSR repair vs. No repair was evaluated on 30-day mortality (p=≤0.01). VSR repair was associated with lower 30-day mortality compared to no repair (51.7% vs 65.7%, P≤0.01), although overall VSR-AMI mortality remained high and unchanged between 1999 and 2014.
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